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Total thyroidal content of iodine in thyrotoxic patients measured by in vivo neutron activation analysis.

Total thyroidal content of iodine in thyrotoxic patients measured by in vivo neutron activation analysis.

Authors :
Robertson I
Boddy K
Hooper MJ
Stevenson RD
McGhie T
Alexander WD
Wilson GM
Source :
Clinical endocrinology [Clin Endocrinol (Oxf)] 1976 Mar; Vol. 5 (2), pp. 151-7.
Publication Year :
1976

Abstract

This paper describes an in vivo method for measuring total thyroidal iodine stores by activation analysis, its evaluation and measurements in thyrotoxic patients. There was good correlation between measurements of solutions of iodine and post-mortem thyroids by activation analysis and chemical analysis. Measurements in thyrotoxic patients showed low levels in untreated and treated (antithyroid drugs) patients and a marked increase in patients studied whilst in clinical remission. The practical importance of this method of measurement of thyroidal iodine stores is that it is a reliable in vivo measurement obtained at a single visit and should enable the definition of the relationship of thyroidal iodine stores to pathophysiology and prognosis.

Details

Language :
English
ISSN :
0300-0664
Volume :
5
Issue :
2
Database :
MEDLINE
Journal :
Clinical endocrinology
Publication Type :
Academic Journal
Accession number :
1269161
Full Text :
https://doi.org/10.1111/j.1365-2265.1976.tb02826.x