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[Preparation of some pyrido (2,3-e)-1,4-diazepines].
- Source :
-
Il Farmaco; edizione scientifica [Farmaco Sci] 1976 May; Vol. 31 (5), pp. 322-33. - Publication Year :
- 1976
-
Abstract
- By treating pyrido (2,3-e)-1,4-diazepinones with alkyl halides, N4-alkylpyrido (2,3-e)-1,4-diazepines were obtained. In addition a number of N1-alkylpyrido (2,3-e)-1,4-diazepines were prepared from alkyltetrahydronaphthyridinones by the Schmidt reaction. Preliminary pharmacological screening of some of these compounds showed no appreciable activity.
- Subjects :
- Animals
Azepines pharmacology
Cardiovascular System drug effects
Central Nervous System drug effects
Drug Evaluation, Preclinical
Indicators and Reagents
Magnetic Resonance Spectroscopy
Pyridines pharmacology
Spectrophotometry, Infrared
Azepines chemical synthesis
Pyridines chemical synthesis
Subjects
Details
- Language :
- Italian
- ISSN :
- 0430-0920
- Volume :
- 31
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Il Farmaco; edizione scientifica
- Publication Type :
- Academic Journal
- Accession number :
- 1269736
- Full Text :
- https://doi.org/10.1002/chin.197637272