Back to Search Start Over

Absolute configuration and complete assignment of 13C NMR data for new sesquiterpenes from Maytenus chiapensis.

Authors :
Núñez MJ
Cortés-Selva F
Bazzocchi IL
Jiménez IA
González AG
Ravelo AG
Gavin JA
Source :
Journal of natural products [J Nat Prod] 2003 Apr; Vol. 66 (4), pp. 572-4.
Publication Year :
2003

Abstract

Five new dihydro-beta-agarofuran sesquiterpenes (1-5) were isolated from the leaves of Maytenus chiapensis. The structures of 1-5 were determined by means of 1D and 2D NMR techniques. A semiselective HMBC technique was applied in order to obtain complete (13)C NMR assignments. Absolute configurations were determined by CD studies and chemical correlations and on biogenetic grounds. Compound 4 showed weak activity against a multidrug-resistant Leishmania tropica line.

Details

Language :
English
ISSN :
0163-3864
Volume :
66
Issue :
4
Database :
MEDLINE
Journal :
Journal of natural products
Publication Type :
Academic Journal
Accession number :
12713421
Full Text :
https://doi.org/10.1021/np0205248