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[Surgical treatment of tumor metastases in the lungs, brain or liver].

Authors :
van den Berkmortel FW
Ruers TJ
Bootsma GP
Verhagen AF
de Mulder PH
Source :
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2003 May 10; Vol. 147 (19), pp. 904-8.
Publication Year :
2003

Abstract

Metastases are generally an expression of widespread disease and therefore warrant systemic treatment. However, clinical observations have revealed that local surgical treatment might be beneficial in the case of organ-confined metastatic disease. Randomised studies have revealed that in the case of brain metastases, metastasectomy followed by radiotherapy, has a favourable outcome with respect to both the quality of life and overall survival. Retrospective non-randomised studies in selected patient groups show prolonged post-treatment survival in the case of both lung and liver metastasectomy. The most important prognostic factors for metastasectomy are: disease control elsewhere in the body, tumour species, the patient's general condition, and the possibility of a total resection of the metastasis. These factors form the basis of the separate decision-making process for each individual patient.

Details

Language :
Dutch; Flemish
ISSN :
0028-2162
Volume :
147
Issue :
19
Database :
MEDLINE
Journal :
Nederlands tijdschrift voor geneeskunde
Publication Type :
Academic Journal
Accession number :
12768804