Central pontine myelinolysis complicating treatment of multicentric Castleman's disease and Kaposi's sarcoma in a patient with AIDS.

Authors :: Apoola A
Ross J
Duddy MJ
Mudaliar V
Jones EL
Huengsberg M
Miller RF
Source :: Sexually transmitted infections [Sex Transm Infect] 2003 Jun; Vol. 79 (3), pp. 179-84.
Publication Year :: 2003
Abstract: An HIV positive black African woman presented with widespread lymphadenopathy and pancytopenia that had been ascribed to tuberculosis. Lymph node biopsy showed both Kaposi's sarcoma and multicentric Castleman's disease. Despite antiretroviral therapy and chemotherapy the patient deteriorated, developing confusion and dysphasia. A cranial magnetic resonance scan showed central pontine myelinolysis. Despite supportive therapy the patient died.

Subjects :: AIDS-Related Complex complications
AIDS-Related Complex drug therapy
Adult
Castleman Disease complications
Castleman Disease drug therapy
Fatal Outcome
Female
Humans
Magnetic Resonance Imaging
Myelinolysis, Central Pontine complications
Myelinolysis, Central Pontine drug therapy
Sarcoma, Kaposi complications
Sarcoma, Kaposi drug therapy
Tomography, X-Ray Computed
AIDS-Related Complex diagnosis
Castleman Disease diagnosis
Myelinolysis, Central Pontine diagnosis
Sarcoma, Kaposi diagnosis

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