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[The reactivity of the skeletal muscle arterioles of rats to noradrenaline after whole-body gamma irradiation at a dose of 1 Gy].

Authors :
Zakharov AG
Ivanov LS
Khmelevskiĭ EV
Bozhenko VK
Source :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1992 Oct; Vol. 114 (10), pp. 355-7.
Publication Year :
1992

Abstract

Male Wistar rats were exposed by total gamma-irradiation at 1 Gy, Reactions of skeletal muscle arterioles and mean arterial pressure on intravenous doses of noradrenaline (0.1, 0.3, 1.0 and 3.0 micrograms/kg) was studied by intravital microscopy in acute experiments 1, 3 and 5-6 days after irradiation. The exposure causes arterial hypotension on day 1 after that as well as marked reduction of spontaneous arteriole vasomotions and decrease of arteriole constrictions at any doses and dates under study. There are no differences of arterial pressure reaction amplitudes in per cent between control and exposed animals at any doses and dates under investigation.

Details

Language :
Russian
ISSN :
0365-9615
Volume :
114
Issue :
10
Database :
MEDLINE
Journal :
Biulleten' eksperimental'noi biologii i meditsiny
Publication Type :
Academic Journal
Accession number :
1288685