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Coronary intervention with a heparin-coated stent and aspirin only.
- Source :
-
The Journal of invasive cardiology [J Invasive Cardiol] 2003 Aug; Vol. 15 (8), pp. 439-41. - Publication Year :
- 2003
-
Abstract
- Objectives: To determine the safety and efficacy of a post-stenting anti-platelet regimen of aspirin without additional ticlopidine or clopidogrel after successful heparin-coated stent implantation.<br />Methods: A prospective, non-randomized, multi-center pilot study of patients undergoing percutaneous coronary intervention, including those with acute coronary syndromes and small vessels with one-month clinical follow-up, was undertaken. Patients received a heparin-coated stent and were treated with aspirin only.<br />Results: Over a period of 6 months, a total of 122 patients were recruited in 6 centers. Their mean age was 57.2 10.0 years, 79% were male and 31% had unstable angina. Most (75%) had single-vessel disease, predominantly of the left anterior descending artery (51%), with a mean reference diameter of 2.44 mm 0.44 mm at baseline and 2.48 0.41 mm post stenting. At a 1-month clinical follow-up, no major adverse cardiovascular events (including subacute stent thrombosis) had occurred. Five patients were readmitted to hospital for symptoms unrelated to the interventional procedure.<br />Conclusions: Heparin-coated stent implantation using an antiplatelet regimen of aspirin only, appears to be safe and feasible. A randomized trial of a larger number of patients appears warranted.
- Subjects :
- Adult
Aged
Asia epidemiology
Blood Vessel Prosthesis Implantation
Coronary Angiography
Coronary Disease diagnostic imaging
Coronary Disease epidemiology
Female
Humans
Male
Middle Aged
New Zealand epidemiology
Pilot Projects
Postoperative Complications epidemiology
Postoperative Complications etiology
Angioplasty, Balloon, Coronary
Aspirin therapeutic use
Coated Materials, Biocompatible therapeutic use
Coronary Disease therapy
Fibrinolytic Agents therapeutic use
Heparin therapeutic use
Stents
Subjects
Details
- Language :
- English
- ISSN :
- 1042-3931
- Volume :
- 15
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Journal of invasive cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 12890872