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Clinical significance of the polymerase chain reaction (PCR) assay in chronic HBV carriers.
- Source :
-
Archives of virology. Supplementum [Arch Virol Suppl] 1992; Vol. 4, pp. 97-101. - Publication Year :
- 1992
-
Abstract
- PCR was evaluated as a clinical tool for use in accurate identification of the specific etiologic agent in chronic HBV carriers. The method was found to be valuable in diagnosis and for monitoring therapy, as well as for elucidation of genotypic variants of HBV in chronic HBV cases. By this means an HBV defective variant with alterations in the preS1/preS2 sequence was detected and is consequently described here.
- Subjects :
- Asia, Southeastern ethnology
Carcinoma, Hepatocellular etiology
Carrier State
DNA, Viral genetics
Defective Viruses genetics
Defective Viruses isolation & purification
Hepatitis B complications
Hepatitis B genetics
Hepatitis B immunology
Hepatitis B Surface Antigens genetics
Hepatitis, Chronic genetics
Hepatitis, Chronic immunology
Humans
Liver Neoplasms etiology
Male
Protein Precursors genetics
Reproducibility of Results
Viral Envelope Proteins genetics
DNA, Viral blood
Hepatitis B diagnosis
Hepatitis, Chronic diagnosis
Polymerase Chain Reaction
Subjects
Details
- Language :
- English
- ISSN :
- 0939-1983
- Volume :
- 4
- Database :
- MEDLINE
- Journal :
- Archives of virology. Supplementum
- Publication Type :
- Academic Journal
- Accession number :
- 1333334
- Full Text :
- https://doi.org/10.1007/978-3-7091-5633-9_21