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Synthesis and antimycobacterial activity of (3,4-diaryl-3H-thiazol-2-ylidene)-hydrazide derivatives.

Authors :
Mamolo MG
Falagiani V
Zampieri D
Vio L
Banfi E
Scialino G
Source :
Farmaco (Societa chimica italiana : 1989) [Farmaco] 2003 Sep; Vol. 58 (9), pp. 631-7.
Publication Year :
2003

Abstract

[5-(pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid (3,4-diaryl-3H-thiazol-2-ylidene)-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed an interesting activity against a strain of Mycobacterium tuberculosis H(37)Rv and three clinical isolates of M. tuberculosis.

Details

Language :
English
ISSN :
0014-827X
Volume :
58
Issue :
9
Database :
MEDLINE
Journal :
Farmaco (Societa chimica italiana : 1989)
Publication Type :
Academic Journal
Accession number :
13679155
Full Text :
https://doi.org/10.1016/S0014-827X(03)00103-4