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Vermixocins A and B, two novel metabolites from Penicillium vermiculatum.
- Source :
-
The Journal of antibiotics [J Antibiot (Tokyo)] 1992 Aug; Vol. 45 (8), pp. 1268-72. - Publication Year :
- 1992
-
Abstract
- Vermixocins A and B, 3-(1'-hydroxy-3'-methylbutyl)- and 3-(1'-acetoxy-3'-methylbutyl)-11-hydroxy-4-methoxy-9-methyl-5H,7H- dibenzo[c,f][1,5]dioxocin-5-one, respectively, were isolated from the mycelium of Penicillium vermiculatum. Both metabolites showed cytotoxic effects on lympholeukemia cells P388.
- Subjects :
- Animals
Antibiotics, Antineoplastic chemistry
Antibiotics, Antineoplastic pharmacology
Heterocyclic Compounds chemistry
Heterocyclic Compounds isolation & purification
Leukemia P388 metabolism
Mice
Antibiotics, Antineoplastic isolation & purification
Heterocyclic Compounds, 3-Ring
Penicillium metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0021-8820
- Volume :
- 45
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 1399847
- Full Text :
- https://doi.org/10.7164/antibiotics.45.1268