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[Effect of extensiveness of testicular germinoma on the choice of a treatment regimen].
- Source :
-
Voprosy onkologii [Vopr Onkol] 2003; Vol. 49 (4), pp. 455-8. - Publication Year :
- 2003
-
Abstract
- Complex examination and treatment were given to 282 patients with testicular germ cell cancer. Diagnosis was histologically verified in all cases. Metastases at different sites were identified in 136 (48.2%). Seminoma was treated with telegamma radiation from the ROCUS-M installation; cases of non-seminoma pathology received VAB-6 and BEP regimes. Germ cell cancer staging was facilitated by joint use of up-to-date diagnostic procedures. X-ray examination of organs of the chest was performed in all cases and sometimes supplemented with CT. Ultrasound, CT and MRI were chiefly used for diagnosis of pathologies of the abdominal cavity and retroperitoneal space. Prognosis and chemotherapy regimes were based on tumor stage assessment. After therapy, recurrence-free cases and those with total regression were released from hospital. Oncological follow-up included tumor marker monitoring and dynamic X-ray examination of the chest, abdominal cavity and retroperitioneal space. When metastasis regression was not complete, surgery was indicated, if technically feasible.
- Subjects :
- Abdominal Neoplasms secondary
Abdominal Neoplasms therapy
Adolescent
Adult
Biomarkers, Tumor blood
Chemotherapy, Adjuvant
Germinoma blood
Germinoma drug therapy
Germinoma radiotherapy
Germinoma secondary
Humans
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Radiotherapy, Adjuvant
Retroperitoneal Neoplasms secondary
Retroperitoneal Neoplasms therapy
Seminoma pathology
Seminoma therapy
Testicular Neoplasms blood
Testicular Neoplasms drug therapy
Testicular Neoplasms radiotherapy
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Germinoma pathology
Germinoma therapy
Testicular Neoplasms pathology
Testicular Neoplasms therapy
Subjects
Details
- Language :
- Russian
- ISSN :
- 0507-3758
- Volume :
- 49
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Voprosy onkologii
- Publication Type :
- Academic Journal
- Accession number :
- 14569936