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Serological studies of monoclonal RH antibodies with RH1 (D), RH2 (C), RH3 (E) and RH5 (e) variant RBCs.
- Source :
-
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2003 Oct; Vol. 10 (5), pp. 319-23. - Publication Year :
- 2003
-
Abstract
- One hundred and forty five Mabs against RH antigens were tested. In this paper, we chose to detail reactivity of MoAbs directed against variant RBCs of the CNRGS collection for which we studied the molecular background. Because we developed procedures to identify variants of the RhD, RhC, RhE and Rhe antigens, we were especially interested in finding new monoclonal antibodies that could help us to characterize more accurately these variants. Therefore, we drew parallels between our procedures and results obtained with the 2001 workshop antibodies.
- Subjects :
- Antibody Specificity
Antigen-Antibody Reactions
Blood Grouping and Crossmatching standards
Coombs Test
Erythrocyte Membrane immunology
Genetic Variation
Hemagglutination Tests
Humans
Immunoglobulin G immunology
Immunoglobulin M immunology
Rh-Hr Blood-Group System genetics
Serology standards
Antibodies, Monoclonal immunology
Rh-Hr Blood-Group System immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1246-7820
- Volume :
- 10
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
- Publication Type :
- Academic Journal
- Accession number :
- 14572547
- Full Text :
- https://doi.org/10.1016/s1246-7820(03)00106-x