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Chronic lithium nephropathy: MR imaging for diagnosis.
- Source :
-
Radiology [Radiology] 2003 Nov; Vol. 229 (2), pp. 570-4. - Publication Year :
- 2003
-
Abstract
- Purpose: To evaluate the appearance of lithium nephropathy at magnetic resonance (MR) imaging.<br />Materials and Methods: Sixteen patients with renal insufficiency and clinical and laboratory evidence of nephropathy secondary to therapy with lithium salts were examined with a 1.5-T MR imaging unit with T1-weighted, T2-weighted fast imaging with steady-state precession (true FISP), rapid acquisition with relaxation enhancement, half-Fourier turbo spin-echo, and gadolinium-enhanced (FISP three-dimensional MR angiographic) sequences. Renal size and the presence, number, location and size of parenchymal cysts were analyzed. The cysts in each kidney were defined as rare (fewer than 10 cysts), sparse (between 10 and 30 cysts), abundant (30-60 cysts), or very abundant (more than 60 cysts).<br />Results: The mean length of both kidneys was 104 mm +/- 9 in seven cases, and one or both kidneys were less than 90 mm in length in nine cases. Renal microcysts measuring from 1 to 2 mm were detected in all patients. They were either very abundant (n = 12), abundant (n = 2), or sparse (n = 2). The cysts were located with equal abundance in both the cortex and the medulla in 11 cases and were predominantly located in the renal cortex in five cases. No renal artery stenosis was present.<br />Conclusion: Microcysts secondary to long-term lithium therapy can be detected with MR imaging.<br /> (Copyright RSNA, 2003)
- Subjects :
- Aged
Chronic Disease
Female
Humans
Kidney pathology
Kidney Diseases, Cystic chemically induced
Kidney Diseases, Cystic diagnosis
Kidney Failure, Chronic chemically induced
Kidney Failure, Chronic diagnosis
Magnetic Resonance Angiography
Male
Middle Aged
Renal Artery pathology
Retrospective Studies
Kidney Diseases chemically induced
Kidney Diseases diagnosis
Lithium Compounds adverse effects
Magnetic Resonance Imaging
Subjects
Details
- Language :
- English
- ISSN :
- 0033-8419
- Volume :
- 229
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 14595154
- Full Text :
- https://doi.org/10.1148/radiol.2292020758