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Oral manifestations of paracoccidioidomycosis. Report of 21 cases from Argentina.
Oral manifestations of paracoccidioidomycosis. Report of 21 cases from Argentina.
- Source :
-
Mycoses [Mycoses] 2003; Vol. 46 (9-10), pp. 412-7. - Publication Year :
- 2003
-
Abstract
- The present study describes 21 Argentinian patients living in the province of Corrientes, who had developed oral manifestations due to Paracoccidioides brasiliensis infection. Of these, 20 patients were men and one a woman. Patients were of an average age of 39 years (range 25 to 72 years). Approximately, 76.2% of the patients were farmers. Gingival lesions were observed in 76%. Also, the tongue (71%) and the lips (62%) were frequently affected. Cytological smears and histopathology showed the characteristic fungal cells with the characteristic granulomatous inflammatory reaction consisting of lymphocytes, epithelioid cells and giant cells of the Langhans type. All patients except one had detectable pulmonary involvement. Therapy consists of long-term administration of itraconazole. Oral manifestations of paracoccidioidomycosis are characteristic in their clinical presentation. Early diagnosis and adequate therapy may prevent extensive tissue destructions. Long-term follow-up is mandatory.
- Subjects :
- Adult
Aged
Antifungal Agents pharmacology
Antifungal Agents therapeutic use
Argentina epidemiology
Female
Humans
Itraconazole pharmacology
Itraconazole therapeutic use
Ketoconazole pharmacology
Ketoconazole therapeutic use
Lung Diseases, Fungal microbiology
Lymph Nodes microbiology
Male
Middle Aged
Nose Diseases microbiology
Mouth Diseases microbiology
Paracoccidioidomycosis diagnosis
Paracoccidioidomycosis drug therapy
Paracoccidioidomycosis pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0933-7407
- Volume :
- 46
- Issue :
- 9-10
- Database :
- MEDLINE
- Journal :
- Mycoses
- Publication Type :
- Academic Journal
- Accession number :
- 14622391
- Full Text :
- https://doi.org/10.1046/j.0933-7407.2003.00917.x