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[Primary adenocarcinoma of the small intestine].
- Source :
-
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2003 Nov 01; Vol. 147 (44), pp. 2149-53. - Publication Year :
- 2003
-
Abstract
- Three patients, a woman aged 46 years and two men aged 81 and 62 years, presented with abdominal pain, nausea, vomiting and/or weight loss. A small intestine follow-through series revealed a significant stenosis in all 3 patients. A laparotomic partial resection of the affected jejunum and corresponding mesentery was performed. A primary adenocarcinoma of the small intestine was diagnosed; pathology revealed that the resections were radical, and pT3N0, pT2N0 and pT3N0 stage tumours respectively. The first patient underwent a repeat operation four months later due to similar complaints caused by a tumour recurrence; fifteen months later she died from recurrent disease. The second patient was disease-free 3 years after surgery. In the third patient, liver and peritoneal metastases developed 16 months after surgery; he died 10 months after palliative chemotherapy had been initiated. Adenocarcinoma of the small intestine is a rare disease and patients often present late with aspecific complaints. This, combined with the fact that these tumours tend to follow an aggressive course, results in a poor five-year survival rate of 10-35%. Surgery is the only curative treatment currently available. A greater awareness of this type of tumour is needed for treatment results to improve.
- Subjects :
- Abdominal Pain etiology
Adenocarcinoma pathology
Adenocarcinoma surgery
Aged
Aged, 80 and over
Constriction, Pathologic etiology
Fatal Outcome
Female
Humans
Intestinal Neoplasms pathology
Intestinal Neoplasms surgery
Male
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Staging
Prognosis
Weight Loss
Adenocarcinoma diagnosis
Intestinal Neoplasms diagnosis
Subjects
Details
- Language :
- Dutch; Flemish
- ISSN :
- 0028-2162
- Volume :
- 147
- Issue :
- 44
- Database :
- MEDLINE
- Journal :
- Nederlands tijdschrift voor geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 14626829