Back to Search
Start Over
Polymer-assisted solution phase synthesis of the antihyperglycemic agent Rosiglitazone (Avandia).
- Source :
-
Organic & biomolecular chemistry [Org Biomol Chem] 2003 Dec 21; Vol. 1 (24), pp. 4392-5. Date of Electronic Publication: 2003 Nov 06. - Publication Year :
- 2003
-
Abstract
- The commercially important antihyperglycemic agent Rosiglitazone 1(Avandia) has been prepared in high purity by a multi-step, polymer-assisted solution phase (PASP) synthesis without the need for the conventional chromatographic purification of any intermediates.
- Subjects :
- Hypoglycemic Agents isolation & purification
Models, Chemical
Molecular Structure
Polymers chemistry
Rosiglitazone
Solutions chemistry
Thiazolidinediones isolation & purification
Combinatorial Chemistry Techniques methods
Hypoglycemic Agents chemical synthesis
Thiazolidinediones chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1477-0520
- Volume :
- 1
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Organic & biomolecular chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 14685311
- Full Text :
- https://doi.org/10.1039/b307549d