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Microwaves in drug discovery and multi-step synthesis.

Authors :
Alexandre FR
Domon L
Frère S
Testard A
Thiéry V
Besson T
Source :
Molecular diversity [Mol Divers] 2003; Vol. 7 (2-4), pp. 273-80.
Publication Year :
2003

Abstract

The interest of microwaves in drug discovery and multi-step synthesis is exposed with the aim of describing our strategy. These studies are connected with our work on the synthesis of original heterocyclic compounds with potential pharmaceutical value. Reactions in the presence of solvent and solvent-free synthesis can be realised under a variety of conditions; for some of these selected results are given, and where available, results from comparison with the same solvent-free conditions but with classical heating are given.

Details

Language :
English
ISSN :
1381-1991
Volume :
7
Issue :
2-4
Database :
MEDLINE
Journal :
Molecular diversity
Publication Type :
Academic Journal
Accession number :
14870858
Full Text :
https://doi.org/10.1023/b:modi.0000006860.56083.2b