[Experimental study on attachment of bacillus Calmette-Guerin to bladder wall with different types of injury].

Authors :: Ding GQ
Shen ZJ
Chen ZD
Source :: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences [Zhejiang Da Xue Xue Bao Yi Xue Ban] 2004 Jan; Vol. 33 (1), pp. 65-7.
Publication Year :: 2004
Abstract: Objective: To investigate whether different types of injury on bladder wall can influence bacillus Calmette-Guerin (BCG) attachment.<br />Methods: The bladder mucosa of 24 rabbits were treated by electrocautery,cryocautery and incision on left lateral wall, right lateral wall and posterior wall, respectively. Then radiolabeled BCG ((3)H-BCG) was instilled into bladder. Two hours latter, the injured bladder wall with different methods and non-injured wall (anterior wall of bladder) were surgically removed and digested. The quantity of BCG of each specimen was determined by liquid scintillation counter.<br />Result: The quantity of BCG attachment to bladder wall with different injuries was significantly higher than that of non-injured wall (P<0.001), meanwhile there was no statistically difference among the BCG levels of different injury types (P>0.05).<br />Conclusion: BCG attachment is not influenced by different types of injury on the bladder wall.

Subjects :: Animals
Female
Male
Rabbits
Bacterial Adhesion
Mycobacterium bovis physiology
Urinary Bladder injuries
Urinary Bladder microbiology

Language :: Chinese
ISSN :: 1008-9292
Volume :: 33
Issue :: 1
Database :: MEDLINE
Journal :: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Publication Type :: Academic Journal
Accession number :: 14966944
Full Text :: https://doi.org/10.3785/j.issn.1008-9292.2004.01.015

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