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Risk factors for intracranial hemorrhage and nonhemorrhagic stroke after fibrinolytic therapy (from the GUSTO-i trial).
- Source :
-
The American journal of cardiology [Am J Cardiol] 2004 Feb 15; Vol. 93 (4), pp. 458-61. - Publication Year :
- 2004
-
Abstract
- Of 592 patients in the Global Utilization of Streptokinase and tPA for Occluded Arteries-I trial who had a stroke during initial hospitalization, the risk for intracranial hemorrhage was significantly greater in those with recent facial or head trauma (odds ratio 13.0, 95% confidence interval 3.4 to 85.5); dementia was additionally associated with an increased risk for intracranial hemorrhage (odds ratio 3.4, 95% confidence interval 1.2 to 10.2). Because facial or head trauma may greatly influence treatment decisions, this risk factor should be incorporated into models designed to estimate the risks and benefits of fibrinolytic therapy.
- Subjects :
- Aged
Case-Control Studies
Chi-Square Distribution
Female
Humans
Intracranial Hemorrhages etiology
Male
Middle Aged
Odds Ratio
Prospective Studies
Risk Factors
Streptokinase therapeutic use
Stroke etiology
Tissue Plasminogen Activator therapeutic use
Intracranial Hemorrhages epidemiology
Myocardial Infarction drug therapy
Streptokinase adverse effects
Stroke epidemiology
Thrombolytic Therapy adverse effects
Tissue Plasminogen Activator adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9149
- Volume :
- 93
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The American journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 14969623
- Full Text :
- https://doi.org/10.1016/j.amjcard.2003.10.043