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Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases.
- Source :
-
Biochimica et biophysica acta [Biochim Biophys Acta] 2004 Mar 01; Vol. 1644 (2-3), pp. 149-58. - Publication Year :
- 2004
-
Abstract
- Bcl-2 family members are central to the control of cell survival. Work of the last years has established that the function of these proteins can be regulated by mitogenic signaling cascades. Within the scope of this review, we will discuss the contribution of Bcl-2-dependent signaling pathways to cell survival by Raf kinases and also address the underlying mechanisms.
Details
- Language :
- English
- ISSN :
- 0006-3002
- Volume :
- 1644
- Issue :
- 2-3
- Database :
- MEDLINE
- Journal :
- Biochimica et biophysica acta
- Publication Type :
- Academic Journal
- Accession number :
- 14996499
- Full Text :
- https://doi.org/10.1016/j.bbamcr.2003.10.015