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Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.

Authors :
Wuchter C
Richter S
Oltersdorf D
Karawajew L
Ludwig WD
Tamm I
Source :
Haematologica [Haematologica] 2004 Mar; Vol. 89 (3), pp. 363-4.
Publication Year :
2004

Abstract

Distinct expression patterns of pro- and anti-apoptotic proteins may contribute to different prognoses and therapy outcomes in adult versus childhood acute myeloid leukemia (AML). Therefore, we investigated whether expression levels of apoptosis-related proteins CD95, Bcl-2, Bax, Bcl-xL, procaspase-3, XIAP, cIAP-1, and survivin differ between children and adults with de novo AML.

Details

Language :
English
ISSN :
1592-8721
Volume :
89
Issue :
3
Database :
MEDLINE
Journal :
Haematologica
Publication Type :
Report
Accession number :
15020280