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An investigation of the effect of midazolam on the pain experience.

Authors :
Coulthard P
Rood JP
Source :
The British journal of oral & maxillofacial surgery [Br J Oral Maxillofac Surg] 1992 Aug; Vol. 30 (4), pp. 248-51.
Publication Year :
1992

Abstract

In a randomised, double-blind, cross-over study on 20 healthy human volunteers, the effect of intravenous midazolam on pain tolerance using the 'submaximum effort tourniquet technique' is described. Intravenous midazolam administered in conscious sedation doses was found to significantly reduce the affective and motivational component of the pain experience.

Subjects

Subjects :
Adult
Conscious Sedation
Double-Blind Method
Female
Humans
Infusions, Intravenous
Male
Midazolam administration & dosage
Pain physiopathology
Pain Measurement methods
Time Factors
Midazolam therapeutic use
Pain prevention & control

Details

Language :
English
ISSN :
0266-4356
Volume :
30
Issue :
4
Database :
MEDLINE
Journal :
The British journal of oral & maxillofacial surgery
Publication Type :
Academic Journal
Accession number :
1510899
Full Text :
https://doi.org/10.1016/0266-4356(92)90268-n
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