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Prevalence and exoenzyme secretion by Candida albicans isolates from oral and vaginal mucosas of HIV-infected women.
- Source :
-
Mycopathologia [Mycopathologia] 2004 Apr; Vol. 157 (3), pp. 255-61. - Publication Year :
- 2004
-
Abstract
- A cross-sectional study was performed to evaluate the prevalence and the aetiology of forms of mucosal fungal infections of HIV-negative and HIV-positive women. Candida albicans was the predominate specie isolated from both groups of patients, with remarkable proportion of isolation from symptomatic women. All 239 C. albicans isolates, regardless of their source, showed activity of proteinase and phospholipase. It was verified that isolates with particularly higher levels of exoenzymes production were significantly more common in HIV-positive patients. However, isolates obtained from the HIV-positive patients in use of HAART, with protease inhibitor, presented lower levels of these exoenzymes, similar to the levels observed in the isolates from HIV-negative patients.
- Subjects :
- Adolescent
Adult
Antiretroviral Therapy, Highly Active
Brazil epidemiology
Candida albicans immunology
Candida albicans isolation & purification
Candida albicans physiology
Candidiasis complications
Candidiasis epidemiology
Candidiasis immunology
Cross-Sectional Studies
Endopeptidases metabolism
Female
HIV Infections complications
HIV Infections epidemiology
HIV Infections immunology
Humans
Middle Aged
Mouth Mucosa microbiology
Phospholipases antagonists & inhibitors
Phospholipases metabolism
Prevalence
Protease Inhibitors pharmacology
Vagina microbiology
Candida albicans enzymology
Candidiasis microbiology
HIV Infections microbiology
HIV-1 immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0301-486X
- Volume :
- 157
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Mycopathologia
- Publication Type :
- Academic Journal
- Accession number :
- 15180151
- Full Text :
- https://doi.org/10.1023/b:myco.0000024173.02010.a5