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[An epidemiological study on sexual transmission of human immunodeficiency virus among pre-marital group in Yining city, Xinjiang].
- Source :
-
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi [Zhonghua Liu Xing Bing Xue Za Zhi] 2004 Apr; Vol. 25 (4), pp. 322-4. - Publication Year :
- 2004
-
Abstract
- Objective: To study the human immunodeficiency virus (HIV) status through heterosexual transmission in Yining city and to provide information on effective intervention measures.<br />Methods: Cohort of HIV sero-discordant couples identified from 1997 to 2000 was formed. Proportional risk model was used to analyze the time of HIV sero-conversion and the related factors. All the recruiters were under informed consent.<br />Results: Through following on 22 sero-discordant couples, we found that the incidence density (ID) of HIV sero-conversion was 32.49/100 person-year (PY) with 33.74/100 PY for women. In the proportional hazard model, the course of sero-conversion was only 2.43 years and the frequency of sexual contact was statistically significant (>or= 3 times/week vs. < 3 time/week: RR = 1.984, 95% CI: 1.045 - 3.767), indicating this factor was related to the hazard of HIV sero-conversion. However, the viral load of HIV infections has no such effect on HIV sero-conversion of their spouses. In addition, the ratio of CD4(+)/CD8(+) was lower in spouses of HIV sero-conversion than that in spouses of HIV non-sero conversion (t test: t = 4.77, P < 0.01).<br />Conclusion: In order to control HIV transmission among general population, we suggested that HIV/AIDS counseling and testing be developed for pre-marital people in the region with high HIV prevalence.
- Subjects :
- Blotting, Western
China epidemiology
Enzyme-Linked Immunosorbent Assay
Female
HIV Infections immunology
Humans
Incidence
Male
Proportional Hazards Models
Sexual Behavior
Sexually Transmitted Diseases, Viral immunology
HIV immunology
HIV Infections epidemiology
Sexually Transmitted Diseases, Viral epidemiology
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0254-6450
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
- Publication Type :
- Academic Journal
- Accession number :
- 15231201