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[Effects of experimental varicocele on mitochondria calcium and cytochrome C of the epididymis in adolescent rats].
- Source :
-
Zhonghua nan ke xue = National journal of andrology [Zhonghua Nan Ke Xue] 2004 Jun; Vol. 10 (6), pp. 420-2. - Publication Year :
- 2004
-
Abstract
- Objective: To investigate the effects of experimental varicocele on mitochondria calcium and cytochrome C of the epididymal cells in adolescent rats.<br />Methods: Forty male adult Wistar rats were divided into two groups randomly: varicocele group (VG) and sham operation group (SOG) by partial ligation or exposure of the left renal vein. Bilateral epididymides were removed after ten<br />Results: The content of mitochondria weeks. Mitochondria calcium and cytochrome C levels of the epididymal cells were detected. calcium decreased (P < 0.001 ) while that of cytochrome C increased (P < 0.05) markedly in the experimental group compared with SOG.<br />Conclusion: Calcium dyshomeostasis and mitochondrial damage of the epididymal cells caused by varicocele may play an important role in leading to subfertility.
Details
- Language :
- Chinese
- ISSN :
- 1009-3591
- Volume :
- 10
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Zhonghua nan ke xue = National journal of andrology
- Publication Type :
- Academic Journal
- Accession number :
- 15267203