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Effect of a lipid pool on stress/strain distributions in stenotic arteries: 3-D fluid-structure interactions (FSI) models.
- Source :
-
Journal of biomechanical engineering [J Biomech Eng] 2004 Jun; Vol. 126 (3), pp. 363-70. - Publication Year :
- 2004
-
Abstract
- Nonlinear 3-D models with fluid-structure interactions (FSI) based on in vitro experiments are introduced and solved by ADINA to perform flow and stress/strain analysis for stenotic arteries with lipid cores. Navier-Stokes equations are used as the governing equations for the fluid. Hyperelastic Mooney-Rivlin models are used for both the arteries and lipid cores. Our results indicate that critical plaque stress/strain conditions are affected considerably by stenosis severity, eccentricity, lipid pool size, shape and position, plaque cap thickness, axial stretch, pressure, and fluid-structure interactions, and may be used for possible plaque rupture predictions.
- Subjects :
- Animals
Blood Flow Velocity
Blood Physiological Phenomena
Blood Pressure
Cattle
Computer Simulation
Constriction, Pathologic physiopathology
Elasticity
Humans
Shear Strength
Stress, Mechanical
Arteriosclerosis physiopathology
Carotid Arteries physiology
Carotid Stenosis physiopathology
Hemorheology methods
Lipid Metabolism
Models, Cardiovascular
Subjects
Details
- Language :
- English
- ISSN :
- 0148-0731
- Volume :
- 126
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of biomechanical engineering
- Publication Type :
- Academic Journal
- Accession number :
- 15341174
- Full Text :
- https://doi.org/10.1115/1.1762898