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Using a system-on-a-chip implantable device to filter circulating infected cells in blood or lymph.
- Source :
-
IEEE transactions on nanobioscience [IEEE Trans Nanobioscience] 2003 Mar; Vol. 2 (1), pp. 6-13. - Publication Year :
- 2003
-
Abstract
- This paper describes a system on a chip (SoC) that makes use of nanoscale cellular adhesion mechanisms in an integrated electronic microsystem to filter infected cells from blood or lymph. An example of a human immunodeficiency virus-specific SoC is explored in depth. Such systems work in vivo, and blood and lymph are filtered on a continuous basis. With the intelligence on the chip, captured cells can be identified and lyzed, expelled, or otherwise acted upon. These types of systems transfer the burden of research from traditional chemotherapy to bioengineering and system design.
- Subjects :
- Animals
Biosensing Techniques methods
Blood Component Removal methods
Cell Adhesion
Cell Separation methods
Coated Materials, Biocompatible chemistry
Equipment Design
Humans
Infections pathology
Infections therapy
Microdialysis instrumentation
Microdialysis methods
Nanotechnology instrumentation
Nanotechnology methods
Systems Integration
Ultrafiltration methods
Biosensing Techniques instrumentation
Blood Cells pathology
Blood Component Removal instrumentation
Cell Separation instrumentation
Lymph cytology
Prostheses and Implants
Ultrafiltration instrumentation
Subjects
Details
- Language :
- English
- ISSN :
- 1536-1241
- Volume :
- 2
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- IEEE transactions on nanobioscience
- Publication Type :
- Academic Journal
- Accession number :
- 15382417
- Full Text :
- https://doi.org/10.1109/tnb.2003.810160