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Sequential therapy with caspofungin and fluconazole for Candida albicans infection.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2004 Oct; Vol. 48 (10), pp. 4056-8. - Publication Year :
- 2004
-
Abstract
- A sequential therapy of caspofungin (CAS) and fluconazole (FLC) administration for treatment of Candida albicans infection was investigated. Treatment with CAS followed by FLC was as effective as CAS treatment given alone for the same duration. Our data suggest that switching from CAS to FLC is a potentially explorable therapeutic option for treatment of systemic candidiasis.
- Subjects :
- Animals
Antifungal Agents administration & dosage
Antifungal Agents pharmacology
Candida albicans drug effects
Candidiasis microbiology
Caspofungin
Colony Count, Microbial
Drug Therapy, Combination
Echinocandins
Fluconazole administration & dosage
Fluconazole pharmacology
Humans
Kidney microbiology
Lipopeptides
Male
Mice
Peptides, Cyclic administration & dosage
Peptides, Cyclic pharmacology
Antifungal Agents therapeutic use
Candidiasis drug therapy
Fluconazole therapeutic use
Peptides, Cyclic therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0066-4804
- Volume :
- 48
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 15388480
- Full Text :
- https://doi.org/10.1128/AAC.48.10.4056-4058.2004