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[Hiatal hernia, gastro-oesophageal reflux and oesophagitis: videofluorographic, endoscopic and histopathological correlation].
- Source :
-
Chirurgia italiana [Chir Ital] 2004 Jul-Aug; Vol. 56 (4), pp. 483-8. - Publication Year :
- 2004
-
Abstract
- The aim of the study was to evaluate the correlation between hiatal hernia and gastro-oesophageal reflux and related histological abnormalities in patients without endoscopic oesophagitis. A consecutive series of 78 patients with a history of gastro-oesophageal reflux symptoms and hiatal hernia, as defined by videofluorography combined with a water siphon test, underwent oesophagogastroduodenoscopy and multiple biopsies. Hiatal hernia was confirmed endoscopically in 99% of cases. The water siphon test was positive for reflux in 72% of cases. At endoscopy 42% of patients had oesophagitis and/or Barrett's oesophagus and 58% had no lesions. In the group without endoscopic lesions, at histology oesophagitis-related alterations were found in 98% and intestinal metaplasia in 27%. In conclusion, this study shows that symptomatic gastro-oesophageal reflux patients with radiologically defined hiatal hernia should undergo endoscopy with multiple biopsies above the squamocolumnar junction, even when endoscopy is normal. This is in order to detect histological gastro-oesophageal-reflux-related alterations, above all, when a positive water siphon test is also present, owing to its known correlation with intestinal metaplasia.
- Subjects :
- Adult
Aged
Barrett Esophagus diagnosis
Biopsy
Cineradiography
Diagnosis, Differential
Endoscopy, Gastrointestinal
Esophagitis diagnostic imaging
Esophagitis pathology
Esophagoscopy
Esophagus pathology
Female
Fluoroscopy
Gastroesophageal Reflux diagnostic imaging
Gastroesophageal Reflux pathology
Hernia, Hiatal diagnostic imaging
Hernia, Hiatal pathology
Humans
Male
Metaplasia
Middle Aged
Video Recording
Water administration & dosage
Esophagitis diagnosis
Gastroesophageal Reflux diagnosis
Hernia, Hiatal diagnosis
Subjects
Details
- Language :
- Italian
- ISSN :
- 0009-4773
- Volume :
- 56
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Chirurgia italiana
- Publication Type :
- Academic Journal
- Accession number :
- 15452985