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[Strain-specific antibodies as an indicator of the circulation of wild poliomyelitis viruses and their role in the formation of collective immunity in the population].
- Source :
-
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2004 Jul-Aug (4), pp. 26-31. - Publication Year :
- 2004
-
Abstract
- Essential differences in the intensity of collective immunity to poliomyelitis in the donors of Moscow and Kaluga were established. To find out the nature of high characteristics of collective immunity to poliovirus, types 1 and 2, in the donors of Kaluga, strain-specific antibodies to wild and vaccine polioviruses were studied. In a considerable number of donors strain-specific antibodies to poliovirus, types 1 and 2, were detected. This made it possible to presume a sufficiently wide circulation of these viruses among the population of the city in the middle of the 20th century and, as a consequence, high level of collective immunity appeared. Strain-specific antibodies to poliovirus of type 3 were rarely detected. This made it possible to suggest that the circulation of viruses of this type among the population was limited. Immunity to viruses of this type was due only to immunization. For this reason the characteristics of collective immunity in the donors of Moscow and Kaluga coincided. The detection of strain-specific antibodies to poliomyelitis virus allowed to retrospectively form the opinion of the spread and time of the circulation of wild poliomyelitis viruses in the population.
- Subjects :
- Adolescent
Adult
Antibody Specificity
Blood Donors
Child
Child, Preschool
Humans
Infant
Middle Aged
Poliomyelitis epidemiology
Poliovirus immunology
Poliovirus Vaccine, Oral immunology
Russia epidemiology
Seroepidemiologic Studies
Urban Population
Antibodies, Viral blood
Poliomyelitis blood
Poliovirus isolation & purification
Subjects
Details
- Language :
- Russian
- ISSN :
- 0372-9311
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhurnal mikrobiologii, epidemiologii i immunobiologii
- Publication Type :
- Academic Journal
- Accession number :
- 15481915