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Testicular seminoma after the complete remission of extragonadal yolk sac tumor : a case report.

Authors :
Kuroda I
Ueno M
Mitsuhashi T
Nakagawa K
Yanaihara H
Tsukamoto T
Deguchi N
Source :
BMC urology [BMC Urol] 2004 Nov 16; Vol. 4, pp. 13. Date of Electronic Publication: 2004 Nov 16.
Publication Year :
2004

Abstract

Background: Between 2% and 5% of malignant germ-cell tumors in men arise at extragonadal sites. Of extragonadal germ cell tumors, testicular carcinoma in situ (CIS) are present in 31-42% of cases, and CIS are reported to have low sensitivity to chemotherapy in spite of the various morphology and to have a high likelihood of developing into testicular tumors. A testicular biopsy may thus be highly advisable when evaluating an extragonadal germ cell tumor.<br />Case Presentation: A 36-year-old man was diagnosed as having an extragonadal non-seminomatous germ cell tumor, that was treated by cisplatin-based chemotherapy, leading to a complete remission. In the meantime, testicular tumors were not detected by means of ultrasonography. About 4 years later, a right testicular tumor was found, and orchiectomy was carried out. Microscopically, the tumor was composed of seminoma.<br />Conclusions: We herein report a case of metachronous occurrence of an extragonadal and gonadal germ cell tumor. In the evaluation of an extragonadal germ cell tumor, a histological examination should be included since ultrasonography is not sufficient to detect CIS or minute lesions of the testis.

Details

Language :
English
ISSN :
1471-2490
Volume :
4
Database :
MEDLINE
Journal :
BMC urology
Publication Type :
Academic Journal
Accession number :
15546481
Full Text :
https://doi.org/10.1186/1471-2490-4-13