Decreased levofloxacin susceptibility in Haemophilus influenzae in children, Hong Kong.

Authors :: Ho PL
Chow KH
Mak GC
Tsang KW
Lau YL
Ho AY
Lai EL
Chiu SS
Source :: Emerging infectious diseases [Emerg Infect Dis] 2004 Nov; Vol. 10 (11), pp. 1960-2.
Publication Year :: 2004
Abstract: Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.

Subjects :: Anti-Bacterial Agents pharmacology
Carrier State
Child
Child, Preschool
Hong Kong
Humans
Infant
Nalidixic Acid pharmacology
Nasopharynx microbiology
Drug Resistance, Bacterial
Haemophilus influenzae drug effects
Levofloxacin
Ofloxacin pharmacology

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