Back to Search
Start Over
[Prophylaxis and treatment of adynamic bone].
- Source :
-
Clinical calcium [Clin Calcium] 2004 Sep; Vol. 14 (9), pp. 34-9. - Publication Year :
- 2004
-
Abstract
- The pathogenesis of adynamic bone disease (ABD) attributes to calcium overload, active vitamin D (VD) metabolism, increase in inactive PTH (parathyroid hormone) fragments, or derangement of bone metabolism regulation factors. In particular, increased Ca overload plays a critical role in the development of ABD. Thus, alleviated Ca load by sevelamer hydrochloride and appropriate VD administration could be effective on not only prevention, and also treatment of ABD.
- Subjects :
- Animals
Bone Morphogenetic Protein 7
Bone Morphogenetic Proteins physiology
Bone and Bones metabolism
Carrier Proteins physiology
Chronic Kidney Disease-Mineral and Bone Disorder therapy
Cinacalcet
Glycoproteins physiology
Humans
Hyperparathyroidism, Secondary drug therapy
Hyperparathyroidism, Secondary etiology
Membrane Glycoproteins physiology
Naphthalenes therapeutic use
Osteoprotegerin
Parathyroid Hormone metabolism
Parathyroid Hormone physiology
Polyamines
RANK Ligand
Receptor Activator of Nuclear Factor-kappa B
Receptors, Calcitriol physiology
Receptors, Calcium-Sensing agonists
Receptors, Calcium-Sensing physiology
Receptors, Cytoplasmic and Nuclear physiology
Receptors, Tumor Necrosis Factor
Risk
Sevelamer
Transforming Growth Factor beta physiology
Vitamin D metabolism
Calcium metabolism
Chronic Kidney Disease-Mineral and Bone Disorder etiology
Chronic Kidney Disease-Mineral and Bone Disorder prevention & control
Epoxy Compounds therapeutic use
Polyethylenes therapeutic use
Vitamin D therapeutic use
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0917-5857
- Volume :
- 14
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Clinical calcium
- Publication Type :
- Academic Journal
- Accession number :
- 15577107
- Full Text :
- https://doi.org/CliCa040913341339