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Value of health-related quality of life to predict disability course in multiple sclerosis.
- Source :
-
Neurology [Neurology] 2004 Dec 14; Vol. 63 (11), pp. 2046-50. - Publication Year :
- 2004
-
Abstract
- Objective: To determine the value of health-related quality of life (HRQoL) to predict change in disability status in patients with multiple sclerosis (MS).<br />Methods: Over a 5-year period, data were collected on HRQoL (Medical Outcomes Study Short Form-36 Health Survey) and disability status (Expanded Disability Status Scale) from a heterogeneous group of 81 Dutch-speaking patients with MS.<br />Results: Multivariate logistic regression analysis showed that HRQoL in the domains of Physical Functioning and Role-Physical Functioning is a significant predictor of change in disability status.<br />Conclusions: A patient's subjectively perceived health-related quality of life may not be only a clinically and psychosocially meaningful outcome per se but may also be a predictor of objective outcomes such as change in disability status over a substantial period of time.
- Subjects :
- Adult
Aged
Belgium epidemiology
Disability Evaluation
Disease Progression
Female
Follow-Up Studies
Forecasting
Humans
Logistic Models
Male
Middle Aged
Multiple Sclerosis psychology
Multivariate Analysis
Netherlands epidemiology
Patients psychology
Severity of Illness Index
Surveys and Questionnaires
Multiple Sclerosis epidemiology
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1526-632X
- Volume :
- 63
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 15596748
- Full Text :
- https://doi.org/10.1212/01.wnl.0000145769.51420.ed