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Ultrastructural analysis of the interactions between Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica and human tracheal epithelial cells.
- Source :
-
Microbial pathogenesis [Microb Pathog] 2005 Jan; Vol. 38 (1), pp. 41-6. - Publication Year :
- 2005
-
Abstract
- Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are respiratory pathogens that colonize the respiratory tract of their host after adhesion to the respiratory epithelium. Presently, the intracellular fate of these bacteria in human tracheal epithelial cells was compared by use of transmission electron microscopy. The three species, even when cytotoxic, were taken-up by epithelial cells. Although, some intracellular bacteria appeared morphologically intact and survived a few days inside epithelial cells, most of them appeared quickly degraded, phenomenon which was associated with an intense cell metabolic activity. Even cytotoxic Bordetella species is ultimately killed by human epithelial cells.
- Subjects :
- Bordetella bronchiseptica growth & development
Bordetella parapertussis physiology
Bordetella pertussis physiology
Cytoplasm microbiology
Cytoplasm ultrastructure
Humans
Microscopy, Electron, Transmission
Trachea ultrastructure
Bacterial Adhesion
Bordetella bronchiseptica ultrastructure
Bordetella parapertussis ultrastructure
Bordetella pertussis ultrastructure
Epithelial Cells microbiology
Epithelial Cells physiology
Trachea microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 0882-4010
- Volume :
- 38
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Microbial pathogenesis
- Publication Type :
- Academic Journal
- Accession number :
- 15652294
- Full Text :
- https://doi.org/10.1016/j.micpath.2004.08.003