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Compelling nature of arterial manifestations in Behcet disease.
- Source :
-
Journal of vascular surgery [J Vasc Surg] 2005 Jan; Vol. 41 (1), pp. 53-8. - Publication Year :
- 2005
-
Abstract
- Introduction: We present our experience with surgical treatment of arterial complications in Behcet disease (vasculo-Behcet disease), and the long-term results and pitfalls of surgical treatment.<br />Material and Methods: Between January 1990 and January 2003, 20 consecutive patients underwent surgery to treat vasculo-Behcet disease. Most patients (17 of 20) were men, with mean age of 38.4 years.<br />Results: Thirty-four operations were performed in 20 patients. The operative mortality rate was 5.8% (2 patients). There were 17 emergency operations, 6 because of ruptured primary abdominal aneurysms. There were five others with critical limb ischemia, resulting in 3 amputations. All patients were followed up postoperatively on average for 44 months (range, 6 months-14 years). Two additional patients were lost to follow-up. After the initial operation 10-year survival rate was 30%, 10-year complication-free survival rate was 13%, and 5-year repeat operation-free survival rate was 26%.<br />Conclusion: Although surgical intervention should be postponed until active inflammation has subsided, often this is not possible, because of the emergent nature of these problems. Most arterial complications of vasculo-Behcet disease present with a pseudoaneurysm rupture or with impending rupture. An aggressive surgical approach can be life-saving in such instances, and should be undertaken regardless of long-term complications, which are more common when the operation is performed in the presence of active inflammation. Early and late results can be improved by individualizing, selecting a disease-free area for reconstruction, and eliminating use of autologous graft material.
- Subjects :
- Adult
Aortic Aneurysm, Abdominal surgery
Aortic Rupture surgery
Disease-Free Survival
Emergencies
Female
Follow-Up Studies
Humans
Ischemia surgery
Leg blood supply
Male
Middle Aged
Postoperative Complications
Treatment Outcome
Vascular Diseases mortality
Behcet Syndrome complications
Vascular Diseases etiology
Vascular Diseases surgery
Subjects
Details
- Language :
- English
- ISSN :
- 0741-5214
- Volume :
- 41
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of vascular surgery
- Publication Type :
- Academic Journal
- Accession number :
- 15696044
- Full Text :
- https://doi.org/10.1016/j.jvs.2004.09.018