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Cell size control: new evidence for a general mechanism.

Authors :
Grebien F
Dolznig H
Beug H
Mullner EW
Source :
Cell cycle (Georgetown, Tex.) [Cell Cycle] 2005 Mar; Vol. 4 (3), pp. 418-21. Date of Electronic Publication: 2005 Mar 04.
Publication Year :
2005

Abstract

Continuously proliferating cells have to precisely double their size during each cycle to maintain constant volumes. Time and again, this fact raised questions on the existence of an active cell size control mechanism in eukaryotic cells, which would prevent delayed or premature cell division at inadequate mass. We addressed this open issue by recapitulating in animal cells several long-standing experiments which had identified such a mechanism in yeast.

Details

Language :
English
ISSN :
1551-4005
Volume :
4
Issue :
3
Database :
MEDLINE
Journal :
Cell cycle (Georgetown, Tex.)
Publication Type :
Academic Journal
Accession number :
15703475
Full Text :
https://doi.org/10.4161/cc.4.3.1523