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Two cases of antinuclear antibody negative lupus showing increased proportion of B cells lacking RP105.
- Source :
-
The Journal of rheumatology [J Rheumatol] 2005 Mar; Vol. 32 (3), pp. 562-4. - Publication Year :
- 2005
-
Abstract
- B cells lacking RP105 molecule, a member of the Toll-like receptor family, were increased in the peripheral blood of 2 patients with antinuclear antibody (ANA) negative systemic lupus erythematosus (SLE). The increased proportion of RP105-lacking B cells was associated with disease activity in patients with ANA-negative SLE. When there are no significant serological markers for SLE, analysis of expression of RP105 may be helpful in evaluation of activity in ANA-negative SLE. We describe a new approach, using phenotyping of B cells, to evaluate activity of ANA-negative SLE.
Details
- Language :
- English
- ISSN :
- 0315-162X
- Volume :
- 32
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 15742454