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[Ehrlich tumor cells stimulate T-cell production of interferon-gamma and are resistant to autocrine nitric oxide].

Authors :
Bel'skiĭ IuP
Bel'skaia NV
Danilets MG
Trofimova ES
Patrushev VK
Agafonov VI
Source :
Voprosy onkologii [Vopr Onkol] 2004; Vol. 50 (6), pp. 689-92.
Publication Year :
2004

Abstract

Ehrlich tumor cells released factors which activated T-cell production of interferon-gamma and triggered a mechanism of nitric oxide (NO) production instead of interferon-gamma. When cultured in vitro, they produced NO without stimulation and responded to interferon-gamma by an output rate of NO significantly greater than that in bone marrow cells. Unlike P-815 cells, those of Ehrlich tumor proved resistant to autocrine NO.

Details

Language :
Russian
ISSN :
0507-3758
Volume :
50
Issue :
6
Database :
MEDLINE
Journal :
Voprosy onkologii
Publication Type :
Academic Journal
Accession number :
15755064