Back to Search
Start Over
A prospective study comparing the analgesic efficacy of levobupivacaine, ropivacaine and bupivacaine in pediatric patients undergoing caudal blockade.
- Source :
-
Paediatric anaesthesia [Paediatr Anaesth] 2005 Apr; Vol. 15 (4), pp. 301-6. - Publication Year :
- 2005
-
Abstract
- Background: The aim of our study was to compare postoperative analgesic efficacy, analgesic duration and motor blockade of levobupivacaine, ropivacaine and bupivacaine administered caudally in equal concentrations to children undergoing elective minor surgery.<br />Methods: In the study, 182 children, aged 1-7 years, undergoing either inguinal hernia repair or orchidopexy, were randomly allocated to one of the three groups. They received via a caudal extradural either 1 ml x kg(-1) levobupivacaine 0.2% (Group L) or 1 ml x kg(-1) ropivacaine 0.2% (Group R) or 1 ml x kg(-1) bupivacaine 0.2% (Group B).<br />Results: No statistically significant difference was noted in age, weight, duration of the operation or level of the caudal block between the groups. The onset of analgesia was significantly later after levobupivacaine. Postoperative pain scoring evaluated with Children's and Infant's Postoperative Pain Scale observational scale showed no statistical difference between groups. Median postoperative analgesia was 5.75 h (SEMed: +/- 0.65) in Group L, 5.7 h (SEMed: +/- 0.8) in Group R and 5.35 h (SEMed: +/- 1.3) in Group B the difference being statistically nonsignificant.<br />Conclusions: The degree of motor block was significantly less after ropivacaine and levobupivacaine during the first 2 h postoperatively.
- Subjects :
- Child
Child, Preschool
Digestive System Surgical Procedures
Female
Hemodynamics drug effects
Hernia, Inguinal surgery
Humans
Infant
Male
Motor Neurons drug effects
Oxygen blood
Pain Measurement
Pain, Postoperative epidemiology
Prospective Studies
Ropivacaine
Stereoisomerism
Testis surgery
Amides adverse effects
Anesthesia, Caudal adverse effects
Anesthetics, Local adverse effects
Bupivacaine adverse effects
Bupivacaine chemistry
Nerve Block adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1155-5645
- Volume :
- 15
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Paediatric anaesthesia
- Publication Type :
- Academic Journal
- Accession number :
- 15787921
- Full Text :
- https://doi.org/10.1111/j.1460-9592.2004.01443.x