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The prevalence of the Staphylococcus aureus tst gene among community- and hospital-acquired strains and isolates from Wegener's Granulomatosis patients.
- Source :
-
FEMS microbiology letters [FEMS Microbiol Lett] 2005 Apr 01; Vol. 245 (1), pp. 185-9. - Publication Year :
- 2005
-
Abstract
- To allow rapid identification of toxic shock syndrome toxin-1 (TSST-1)-producing Staphylococcus aureus strains, a real-time PCR assay for the detection of the tst gene, which encodes TSST-1, was developed. The assay was applied to S. aureus isolates from patients with Wegener's Granulomatosis (WG), as well as isolates that were classified as either community- (CA) or hospital-acquired (HA). No significant difference in the percentage of tst-positive strains was observed between isolates from WG patients and CA isolates (24% and 25%, respectively). In contrast, only 14% of the HA isolates were tst-positive (p<0.05). Investigation of the clonal relationship between tst-positive CA and HA strains could indicated the recent emergence of a virulent S. aureus clone in the community.
- Subjects :
- Bacterial Toxins metabolism
Community-Acquired Infections microbiology
Cross Infection microbiology
DNA, Bacterial analysis
Electrophoresis, Gel, Pulsed-Field
Enterotoxins metabolism
Granulomatosis with Polyangiitis microbiology
Humans
Prevalence
Reproducibility of Results
Sensitivity and Specificity
Staphylococcal Infections microbiology
Staphylococcus aureus genetics
Staphylococcus aureus isolation & purification
Superantigens metabolism
Virulence
Bacterial Toxins genetics
Community-Acquired Infections epidemiology
Cross Infection epidemiology
Enterotoxins genetics
Granulomatosis with Polyangiitis epidemiology
Polymerase Chain Reaction methods
Staphylococcus aureus pathogenicity
Superantigens genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0378-1097
- Volume :
- 245
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- FEMS microbiology letters
- Publication Type :
- Academic Journal
- Accession number :
- 15796997
- Full Text :
- https://doi.org/10.1016/j.femsle.2005.03.002