Analysis of VH genes in 49 marginal zone lymphoma cases reveals marked heterogeneity between splenic and nodal tumors and suggests the existence of clonal selection.

Subjects

Subjects :

Animals
Antibody-Producing Cells physiology
Clonal Anergy genetics
Genes, Immunoglobulin physiology
Humans
Lymph Nodes
Lymphatic Diseases blood
Lymphoma, B-Cell blood
Lymphoma, B-Cell immunology
Mice
Mutation drug effects
Neoplasms
Splenic Neoplasms blood
T-Lymphocytes immunology
Immunoglobulin Heavy Chains genetics
Immunoglobulin Variable Region genetics
Lymphatic Diseases genetics
Lymphoma, B-Cell genetics
Splenic Neoplasms genetics

Details

Language :

English

ISSN :

1592-8721

Volume :

90

Issue :

4

Database :

MEDLINE

Journal :

Haematologica

Publication Type :

Academic Journal

Accession number :

15820929