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Synthesis of vaccinia virus polypeptides in the presence of hydroxyurea.
Synthesis of vaccinia virus polypeptides in the presence of hydroxyurea.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 1974 Nov; Vol. 6 (5), pp. 647-50. - Publication Year :
- 1974
-
Abstract
- Hydroxyurea (5 x 10(-3) M) inhibits the development of vaccinia virus in HeLa cells early after infection and prevents the synthesis of viral deoxyribonucleic acid. In the presence of hydroxyurea, late viral polypeptides are not formed, as observed by electrophoresis on polyacrylamide gels.
Details
- Language :
- English
- ISSN :
- 0066-4804
- Volume :
- 6
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 15825321
- Full Text :
- https://doi.org/10.1128/AAC.6.5.647