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Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging.

Authors :
Jun YW
Huh YM
Choi JS
Lee JH
Song HT
Kim S
Yoon S
Kim KS
Shin JS
Suh JS
Cheon J
Source :
Journal of the American Chemical Society [J Am Chem Soc] 2005 Apr 27; Vol. 127 (16), pp. 5732-3.
Publication Year :
2005

Abstract

Since the use of magnetic nanocrystals as probes for biomedical system is attractive, it is important to develop optimal synthetic protocols for high-quality magnetic nanocrystals and to have the systematic understanding of their nanoscale properties. Here we present the development of a synthetically controlled magnetic nanocrystal model system that correlates the nanoscale tunabilities in terms of size, magnetism, and induced nuclear spin relaxation processes. This system further led to the development of high-performance nanocrystal-antibody probe systems for the diagnosis of breast cancer cells via magnetic resonance imaging.

Details

Language :
English
ISSN :
0002-7863
Volume :
127
Issue :
16
Database :
MEDLINE
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
15839639
Full Text :
https://doi.org/10.1021/ja0422155