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[Use of movalis in treatment of dorsopathy].
- Source :
-
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2004; Vol. 104 (12), pp. 29-32. - Publication Year :
- 2004
-
Abstract
- In regard to therapeutic effect of different medications used in dorsopathy treatment, non-steroid anti-inflammatory drugs rank first. Compounds selectively blocking COX-2 received special attention due to their minimal impact on COX-1 that provides good anti-inflammatory and analgesic effect with simultaneous dramatic reduction of ulcerogenic activity. One of the first drugs with such an action is Movalis (meloxicam). Thirty patients were divided into 2 groups, the first including 22 patients with vertebral diseases and musculotonic syndromes; patients of the second group (8) had a pain syndrome caused by disk herniation. During the first 3 days Movalis was administered in the form of injections (15 mg/day) and in the same doses in tablets for the following 20 days. After the treatment course, complete arrest of pain syndrome was observed in 33.3% patients, significant improvement--in 53.3% and insignificant effect--in 13.3%. Patients with reflex pain and musculotonic syndromes had a good analgesic effect after 3-day course of intramuscular injections, with the effect being mostly expressed in 8-10 days. Patients with diskogenic compressive radicular syndrome demonstrated a stable analgesic effect after a week of Movalis intake in tablet form. Movalis is well tolerated; side effects have occurred in 10 patients but they were minimal and did not lead to the change of medication dose or additional therapy.
- Subjects :
- Adult
Aged
Aged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal administration & dosage
Anti-Inflammatory Agents, Non-Steroidal adverse effects
Back Pain diagnosis
Back Pain etiology
Cyclooxygenase Inhibitors administration & dosage
Cyclooxygenase Inhibitors adverse effects
Female
Humans
Injections, Intramuscular
Low Back Pain drug therapy
Male
Meloxicam
Middle Aged
Osteochondritis complications
Pain Measurement
Spondylarthropathies complications
Tablets
Thiazines administration & dosage
Thiazines adverse effects
Thiazoles administration & dosage
Thiazoles adverse effects
Time Factors
Treatment Outcome
Anti-Inflammatory Agents, Non-Steroidal therapeutic use
Back Pain drug therapy
Cyclooxygenase Inhibitors therapeutic use
Intervertebral Disc Displacement drug therapy
Spinal Diseases complications
Thiazines therapeutic use
Thiazoles therapeutic use
Subjects
Details
- Language :
- Russian
- ISSN :
- 1997-7298
- Volume :
- 104
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
- Publication Type :
- Academic Journal
- Accession number :
- 15847323