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Presence of exposed phospholipids in the outer membrane of Vibrio cholerae.
- Source :
-
Journal of general microbiology [J Gen Microbiol] 1992 Apr; Vol. 138 (4), pp. 755-61. - Publication Year :
- 1992
-
Abstract
- Vibrio cholerae 569B was found to be highly sensitive to a wide range of chemicals, particularly hydrophobic compounds and neutral and anionic detergents. The phospholipid profile of the outer membrane was similar to that reported for other Gram-negative bacteria. The lipopolysaccharide (LPS) contained O-antigenic sugars and exhibited heterogeneity. In addition, the LPS moiety was characterized by a relatively low negative charge. Analysis by topological probes revealed the presence of a significant amount of exposed phospholipids in the outer membrane. The reduced negative charge of LPS molecules and the exposed phospholipids present in the outer membrane could be important in the increased permeation of exogenous compounds in V. cholerae.
Details
- Language :
- English
- ISSN :
- 0022-1287
- Volume :
- 138
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of general microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 1588309
- Full Text :
- https://doi.org/10.1099/00221287-138-4-755