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Caspofungin in combination with amphotericin B against Candida glabrata.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2005 Jun; Vol. 49 (6), pp. 2546-9. - Publication Year :
- 2005
-
Abstract
- The effects of caspofungin combined with amphotericin B were investigated with Candida glabrata. Although in vitro experiments showed an indifferent interaction, the combination regimen was the only therapeutic approach yielding organ sterilization in a murine candidemia model.
- Subjects :
- Amphotericin B pharmacology
Animals
Antifungal Agents pharmacology
Candida glabrata growth & development
Candidiasis microbiology
Caspofungin
Colony Count, Microbial
Drug Therapy, Combination
Echinocandins
Fungemia microbiology
Lipopeptides
Male
Mice
Microbial Sensitivity Tests methods
Peptides, Cyclic pharmacology
Treatment Outcome
Amphotericin B therapeutic use
Antifungal Agents therapeutic use
Candida glabrata drug effects
Candidiasis drug therapy
Fungemia drug therapy
Peptides, Cyclic therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0066-4804
- Volume :
- 49
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 15917570
- Full Text :
- https://doi.org/10.1128/AAC.49.6.2546-2549.2005