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Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero.
- Source :
-
Epilepsy research [Epilepsy Res] 2005 Jun; Vol. 65 (1-2), pp. 117-20. - Publication Year :
- 2005
-
Abstract
- Vigabatrin (VGB) is an important treatment option for infantile spasms. Vigabatrin-induced visual field defects are at present the most important safety issue in the use of the drug. The knowledge concerning VGB-associated visual dysfunction in pediatric patients, particularly in those who have been exposed to VGB in utero is limited. We explored ophthalmic and neurologic findings in two children who have been exposed prenatally to VGB.
- Subjects :
- Adult
Child
Epilepsy drug therapy
Female
Functional Laterality
Humans
Male
Neurologic Examination methods
Pregnancy
Reaction Time drug effects
Uterus drug effects
Visual Acuity drug effects
Visual Fields drug effects
Anticonvulsants adverse effects
Prenatal Exposure Delayed Effects
Vigabatrin adverse effects
Vision Disorders etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0920-1211
- Volume :
- 65
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Epilepsy research
- Publication Type :
- Academic Journal
- Accession number :
- 15941649
- Full Text :
- https://doi.org/10.1016/j.eplepsyres.2005.04.001