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[Serum S100 protein and radiation-induced brain injury in astrocytoma patients].

Authors :
Song WS
Guo LB
Hong ZY
Li JJ
Wu J
Source :
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA [Di Yi Jun Yi Da Xue Xue Bao] 2005 Jun; Vol. 25 (6), pp. 723-5.
Publication Year :
2005

Abstract

Objective: To study the value of serum S100 protein in the diagnosis of radiation-induced brain injury in astrocytoma patients.<br />Methods: Serum S100 protein levels were detected by enzyme-linked immunosorbent assay in 86 astrocytoma patients in the course of radiotherapy.<br />Results: The positivity rates of serum S100 protein before, in the middle of and after radiotherapy were 0, 9.3% (8/86) and 19.8% (17/86), respectively, showing significant differences (P<0.05) between these time points for measurement.<br />Conclusion: High levels of serum S100 protein are associated with radiation-induced brain injury in astrocytoma patients and may serve as the marker for early diagnosis of the injury.

Details

Language :
Chinese
ISSN :
1000-2588
Volume :
25
Issue :
6
Database :
MEDLINE
Journal :
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA
Publication Type :
Academic Journal
Accession number :
15958321