[Physical activity and type 2 diabetes].

Muscular exercise promotes glucose utilisation by the skeletal muscle, independently of insulin action, by activating the AMP-activated protein kinase (AMPK). This process is not altered in patients with obesity and/or type 2 diabetes, despite the presence of insulin resistance. Thus, exercise should play a key role in the management of type 2 diabetic patients. Regular physical activity enhances insulin sensitivity, improves glucose control and corrects some cardiovascular risk factors. This paper briefly presents some practical recommendations about physical activity in obese and/or type 2 diabetic patients.